Evidence-Based Medicine · Pharmacology

A confidence interval that crosses 1.0 for a relative risk suggests that:

  1. The result is statistically significant at p<0.05
  2. The intervention is harmful to patients
  3. The result is not statistically significant
  4. The study design is invalid
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Correct answer: The result is not statistically significant

A relative risk of 1.0 means no difference between groups. If the confidence interval includes 1.0, the no-effect value lies within the plausible range of results, so the finding is not statistically significant at the corresponding significance level. It does not mean the study is invalid, only that an effect has not been demonstrated.

Difficulty: Medium Question 8 of 20

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