Parkinson Disease Drugs · Pharmacology

Which drug is considered the most effective treatment for the motor symptoms of Parkinson disease?

  1. Levodopa-carbidopa
  2. Selegiline
  3. Amantadine
  4. Subcutaneous apomorphine
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Correct answer: Levodopa-carbidopa

Levodopa is the precursor of dopamine and can cross the blood-brain barrier, where it is converted to dopamine and gives the greatest improvement in motor symptoms. It is given together with carbidopa in standard therapy.

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