Which pharmacological effect explains the cognitive benefits of donepezil and rivastigmine?
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Correct answer: Enhanced cholinergic neurotransmission
Acetylcholinesterase inhibitors prevent the breakdown of acetylcholine. This enhances cholinergic neurotransmission, which is impaired in Alzheimer disease.
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More Alzheimer Disease Drugs questions
- Which drug class helps protect neurons from excitotoxic damage in Alzheimer disease?
- Which outcome best reflects the goal of pharmacological therapy in Alzheimer disease?
- Which class of drugs is most commonly used as first-line therapy for mild to moderate Alzheimer disease?
- Which drug is an acetylcholinesterase inhibitor used in Alzheimer disease?
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- Which neurotransmitter is primarily deficient in the brains of patients with Alzheimer disease?