Neuromuscular Blockers · Pharmacology

Nondepolarizing neuromuscular blockers produce paralysis by which mechanism?

  1. Irreversible inhibition of acetylcholinesterase
  2. Activation of muscarinic receptors
  3. Competitive antagonism of nicotinic receptors
  4. Destruction of acetylcholine molecules
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Correct answer: Competitive antagonism of nicotinic receptors

Nondepolarizing neuromuscular blockers act as competitive antagonists at nicotinic acetylcholine receptors. By preventing acetylcholine from binding, they inhibit muscle contraction.

Difficulty: Medium Question 8 of 20

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