Ganglionic Blockers · Pharmacology

Orthostatic hypotension is a common effect of ganglionic blockers because they inhibit which system?

  1. Somatic motor nerves to skeletal muscle
  2. Central nervous system reflexes
  3. Sympathetic vasoconstrictor reflexes
  4. Parasympathetic cardiac reflexes
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Correct answer: Sympathetic vasoconstrictor reflexes

Sympathetic reflex vasoconstriction normally helps maintain blood pressure when standing. Ganglionic blockers inhibit this reflex, leading to orthostatic hypotension.

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