Which drug is contraindicated in patients with peptic ulcer disease due to its antipyretic mechanism?
Show answer and explanation
Correct answer: Ibuprofen
Ibuprofen inhibits COX-1, reducing protective gastric prostaglandins. This increases the risk of gastrointestinal irritation and ulceration.
Keep practicing
More Fever Management questions
- Which is the primary goal of antipyretic therapy?
- Which condition requires cautious use of NSAIDs for fever management?
- Which drug reduces fever without affecting platelet aggregation?
- Which mechanism differentiates antipyretics from physical cooling methods?
- Which NSAID is most associated with risk of renal impairment when used for fever in dehydrated patients?
- Which area of the brain is primarily responsible for regulating body temperature during fever?