Aspirin reduces fever primarily by:
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Correct answer: Inhibiting cyclooxygenase and prostaglandin synthesis
Aspirin inhibits cyclooxygenase (COX), decreasing prostaglandin E2 production. Reduced prostaglandin levels lower the hypothalamic set-point, thereby reducing fever.
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More Fever Management questions
- Which adverse effect limits the use of aspirin in viral infections in children?
- Which NSAID is also effective as an antipyretic due to COX inhibition?
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- Which drug has minimal anti-inflammatory activity but is effective as an antipyretic?
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