Precision Medicine · Pathology

A germline BRCA1 mutation primarily increases the risk of:

  1. Colon cancer only
  2. Breast and ovarian cancers
  3. Thyroid carcinoma
  4. Cutaneous melanoma exclusively
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Correct answer: Breast and ovarian cancers

Germline BRCA1 mutations significantly increase the risk of breast and ovarian cancers. Identifying such mutations guides preventive and therapeutic strategies.

Difficulty: Medium Question 14 of 20

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