PCR Techniques · Pathology

Which of the following temperature sequences correctly represents the three main steps of a standard PCR cycle?

  1. 95°C, 72°C, 55°C
  2. 95°C, 55°C, 72°C
  3. 72°C, 95°C, 55°C
  4. 55°C, 72°C, 95°C
Show answer and explanation

Correct answer: 95°C, 55°C, 72°C

A standard PCR cycle consists of denaturation (approx. 95°C), annealing (approx. 55°C), and extension (approx. 72°C). This sequence allows DNA strands to separate, primers to bind, and DNA polymerase to synthesize new strands respectively.

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