Cell-Mediated Immunity · Pathology

Which combination of cytokines promotes the differentiation of Th17 cells?

  1. IL-12 and IL-18
  2. IL-4 and IL-13
  3. IL-6 and TGF-β
  4. IFN-γ and TNF-α
Show answer and explanation

Correct answer: IL-6 and TGF-β

Th17 differentiation is driven by cytokines including IL-6 and TGF-β. Th17 cells are important in mucosal immunity and inflammation.

Difficulty: Medium Question 16 of 20

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