Cell-Mediated Immunity · Pathology

Cytotoxic T lymphocytes induce apoptosis of target cells primarily through:

  1. Antibody production
  2. Perforin and granzyme release
  3. Histamine secretion
  4. Complement activation
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Correct answer: Perforin and granzyme release

CD8+ T cells kill target cells by releasing perforin and granzymes. These molecules trigger apoptosis in infected or malignant cells.

Difficulty: Medium Question 9 of 20

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