During reperfusion injury, the generation of which molecule significantly contributes to additional tissue damage?
Show answer and explanation
Correct answer: Reactive oxygen species
Reperfusion provides oxygen to previously ischemic cells, but damaged mitochondria and infiltrating leukocytes can incompletey reduce this oxygen. This leads to the burst of reactive oxygen species that cause further lipid peroxidation and membrane damage.
Keep practicing
More Cell Injury questions
- Which of the following describes the morphology of apoptosis but NOT necrosis?
- Fatty change (steatosis) is most commonly seen in the liver because the liver is the primary organ for:
- A 60-year-old female with long-standing hypertension shows increased thickness of the left ventricular wall. This is an example of:
- The conversion of columnar ciliated epithelium to stratified squamous epithelium in the trachea of a chronic smoker is called:
- Which pigment is known as the 'wear and tear' pigment, accumulating in aged or atrophic cells?
- Dystrophic calcification occurs in which of the following conditions?