Fine Needle Aspiration Cytology · Pathology

In an FNA of a lymph node, the presence of 'Reed-Sternberg' cells is diagnostic for:

  1. Burkitt lymphoma
  2. Hodgkin lymphoma
  3. Anaplastic large cell lymphoma
  4. Mantle cell lymphoma
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Correct answer: Hodgkin lymphoma

Reed-Sternberg cells (large, multinucleated cells with 'owl-eye' nucleoli) in a polymorphous inflammatory background are the hallmark of Hodgkin Lymphoma. However, because they are often sparse, multiple passes may be required.

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