An FNA of a thyroid nodule reveals 'Orphan Annie eye' nuclei and nuclear grooves. This is most suggestive of:
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Correct answer: Papillary thyroid carcinoma
Orphan Annie eye nuclei (clearing of chromatin), nuclear grooves, and pseudo-inclusions are characteristic cytomorphologic features of Papillary Thyroid Carcinoma. These features allow for high diagnostic accuracy in thyroid FNA.
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