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Bethesda System · Pathology

High-grade squamous intraepithelial lesion (HSIL) in cervical cytology suggests:

  1. Reactive cellular changes
  2. CIN 2 or CIN 3 lesion
  3. Benign inflammatory changes
  4. Squamous metaplasia
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Correct answer: CIN 2 or CIN 3 lesion

HSIL is associated with moderate to severe dysplasia (CIN 2 or CIN 3). It carries a higher risk of progression to invasive carcinoma.

Difficulty: Medium Question 5 of 20

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