Childhood Cancer · NCLEX Exam

A child with ALL is receiving intrathecal chemotherapy for central nervous system (CNS) prophylaxis. The primary rationale is that:

  1. Leukemia almost never involves the CNS in young children
  2. CNS involvement is common yet hidden, so prophylaxis prevents relapse
  3. Intrathecal drugs are given to cure an associated kidney tumor
  4. Intrathecal therapy is used mainly to reduce leukemic bone pain
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Correct answer: CNS involvement is common yet hidden, so prophylaxis prevents relapse

In childhood ALL therapy, CNS-directed treatment is required because leukemic cells can hide in the CNS and later cause relapse if not treated.

Difficulty: Hard Question 9 of 18

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