Blood Transfusion Therapy and Nursing Care · NCLEX Exam

Which signs during transfusion suggest a febrile non-hemolytic transfusion reaction?

  1. Rapid-onset hypotension with severe lower back pain
  2. Fever over 1 °C above baseline, chills, and headache
  3. Severe diffuse itching with widespread urticaria
  4. Immediate central cyanosis with audible wheezing
Show answer and explanation

Correct answer: Fever over 1 °C above baseline, chills, and headache

Febrile non-hemolytic reactions are characterised by fever and chills due to cytokines, and unlike hemolytic reactions do not typically show immediate hemolysis signs.

Difficulty: Medium Question 14 of 20

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