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Gastrointestinal and Hepatic System

Inflammatory Bowel Disease Practice Questions

19 free Inflammatory Bowel Disease practice questions for the NCLEX Exam. Tap an option to answer — you get instant feedback, the correct answer, and a detailed explanation for every question.

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Question 1 of 19 Medium

Which characteristic is most associated with Crohn’s disease?

  1. A Continuous inflammation of colon
  2. B Affects only rectum
  3. C Skip lesions throughout GI tract
  4. D Limited to mucosal layer

Correct answer: Skip lesions throughout GI tract

Crohn’s disease is characterized by skip lesions, meaning areas of diseased bowel are interspersed with healthy tissue. It can affect any part of the gastrointestinal tract.

Question 2 of 19 Medium

Which feature distinguishes ulcerative colitis from Crohn’s disease?

  1. A Transmural inflammation of the bowel wall
  2. B Affects the entire GI tract wall
  3. C Continuous inflammation of colon
  4. D Presence of intestinal fistulas

Correct answer: Continuous inflammation of colon

Ulcerative colitis involves continuous inflammation limited to the colon and rectum. It typically affects only the mucosal layer.

Question 3 of 19 Medium

Which symptom is common in ulcerative colitis?

  1. A Constipation
  2. B Bloody diarrhea
  3. C Dry cough
  4. D Joint stiffness only

Correct answer: Bloody diarrhea

Bloody diarrhea is a hallmark symptom of ulcerative colitis. It results from inflammation and ulceration of the colon lining.

Question 4 of 19 Medium

Which complication is more common in Crohn’s disease?

  1. A Toxic megacolon
  2. B Fistula formation
  3. C Rectal bleeding only
  4. D Colon cancer exclusively

Correct answer: Fistula formation

Crohn’s disease can cause transmural inflammation, leading to fistula formation. This is less common in ulcerative colitis.

Question 5 of 19 Medium

Which diet is recommended during an acute flare of inflammatory bowel disease?

  1. A High-fiber diet
  2. B Low-residue diet
  3. C Increased fat intake
  4. D High-spice diet

Correct answer: Low-residue diet

A low-residue diet reduces bowel stimulation and allows the intestines to rest. It helps decrease symptoms during flare-ups.

Question 6 of 19 Medium

Which medication is commonly used to reduce inflammation in IBD?

  1. A Antibiotics
  2. B Antihistamines
  3. C Thiazide diuretics
  4. D Corticosteroids

Correct answer: Corticosteroids

Corticosteroids reduce inflammation in IBD. They are often used during acute exacerbations.

Question 7 of 19 Medium

Which complication is associated with ulcerative colitis?

  1. A Kidney stones
  2. B Gallstones
  3. C Acute pancreatitis
  4. D Toxic megacolon

Correct answer: Toxic megacolon

Toxic megacolon is a severe complication of ulcerative colitis. It involves dilation of the colon and can be life-threatening.

Question 8 of 19 Medium

Which laboratory finding is common in inflammatory bowel disease?

  1. A High hemoglobin
  2. B Low white blood cells
  3. C Iron-deficiency anemia
  4. D Elevated calcium levels

Correct answer: Iron-deficiency anemia

Chronic blood loss and malabsorption can lead to anemia in IBD patients. Monitoring hemoglobin levels is important.

Question 9 of 19 Medium

Which symptom is more common in Crohn’s disease than ulcerative colitis?

  1. A Rectal bleeding
  2. B Mucus in stool
  3. C Frequent urgency
  4. D Slow weight loss

Correct answer: Slow weight loss

Weight loss is more common in Crohn’s disease due to malabsorption. The disease can affect the small intestine extensively.

Question 10 of 19 Medium

Which nursing intervention is priority during severe diarrhea in IBD?

  1. A Encourage complete fasting from all food and fluids.
  2. B Severely restrict all oral fluids
  3. C Increase dietary fiber and roughage intake
  4. D Monitor fluid and electrolyte balance

Correct answer: Monitor fluid and electrolyte balance

Severe diarrhea can lead to dehydration and electrolyte imbalance. Monitoring and replacing fluids is critical.

Question 11 of 19 Medium

Which extraintestinal manifestation may occur in IBD?

  1. A Hair loss
  2. B Weight gain
  3. C Hearing loss
  4. D Arthritis

Correct answer: Arthritis

IBD can cause systemic effects such as arthritis. These are known as extraintestinal manifestations.

Question 12 of 19 Medium

Which medication class is used to suppress immune response in IBD?

  1. A Immunosuppressants
  2. B Antibiotic therapy
  3. C Antacids
  4. D Antihypertensives

Correct answer: Immunosuppressants

Immunosuppressants reduce immune system activity to control inflammation. They are used in moderate to severe IBD.

Question 13 of 19 Medium

Which surgical procedure may be curative for ulcerative colitis?

  1. A Total colectomy
  2. B Appendectomy
  3. C Gastrectomy
  4. D Cholecystectomy

Correct answer: Total colectomy

Removal of the colon (colectomy) can cure ulcerative colitis. This is because the disease is limited to the colon.

Question 14 of 19 Medium

Which finding is typical in Crohn’s disease?

  1. A Continuous lesions
  2. B Superficial ulcers
  3. C Cobblestone appearance
  4. D Only rectal involvement

Correct answer: Cobblestone appearance

Crohn’s disease often presents with a cobblestone appearance of the intestinal lining. This is due to patchy inflammation.

Question 15 of 19 Medium

Which nutrient deficiency is common in Crohn’s disease?

  1. A Vitamin B12
  2. B Vitamin C
  3. C Vitamin D
  4. D Vitamin K

Correct answer: Vitamin B12

Crohn’s disease often affects the terminal ileum, where vitamin B12 is absorbed. This leads to deficiency.

Question 16 of 19 Medium

Which symptom indicates a possible bowel obstruction in Crohn’s disease?

  1. A Abdominal distension and pain
  2. B Watery, non-bloody diarrhea
  3. C Sudden, unexplained weight gain
  4. D Increased appetite with hunger

Correct answer: Abdominal distension and pain

Inflammation and scarring can lead to bowel obstruction. Symptoms include abdominal pain and distension.

Question 17 of 19 Medium

Which is a priority nursing diagnosis for a patient with IBD?

  1. A Imbalanced nutrition: less than body requirements
  2. B Risk for infection from impaired skin and bowel integrity
  3. C Disturbed sensory perception related to visual changes
  4. D Disturbed sleep pattern from abdominal pain

Correct answer: Imbalanced nutrition: less than body requirements

Malnutrition is common due to poor absorption and reduced intake. Addressing nutritional needs is a priority.

Question 18 of 19 Medium

Which lifestyle modification is recommended for IBD patients?

  1. A Smoking cessation
  2. B Increase alcohol intake
  3. C Avoid exercise
  4. D High-fat diet

Correct answer: Smoking cessation

Smoking worsens Crohn’s disease and increases complications. Quitting smoking improves outcomes.

Question 19 of 19 Medium

Which goal is most important in managing IBD?

  1. A Prevent flares and maintain remission
  2. B Cure the disease
  3. C Eliminate all symptoms completely and permanently
  4. D Avoid all medications

Correct answer: Prevent flares and maintain remission

IBD is a chronic condition with no cure. Management focuses on controlling inflammation and maintaining remission.

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