Metabolic Syndrome and Insulin Resistance · NCLEX Exam

Which of the following is a mechanism by which insulin resistance contributes to hypertension in metabolic syndrome?

  1. Decreased sympathetic nervous system activity
  2. Enhanced endothelial nitric oxide production
  3. Renal sodium retention and increased vascular tone
  4. Total absence of insulin receptors within the kidneys
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Correct answer: Renal sodium retention and increased vascular tone

Insulin resistance and hyperinsulinemia may promote sodium retention and increased sympathetic/vascular tone thereby raising blood pressure.

Difficulty: Medium Question 18 of 20

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