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Cancer and Oncology Nursing

Chemotherapy Agents and Side Effects Practice Questions

20 free Chemotherapy Agents and Side Effects practice questions for the NCLEX Exam, each with the correct answer and a detailed explanation. Open any question below, or take the full set as an interactive quiz.

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All Chemotherapy Agents and Side Effects questions

20 questions
  1. Q1. A nurse monitors a patient receiving doxorubicin for signs of which major adverse effect?
  2. Q2. A patient receiving cyclophosphamide should be encouraged to increase fluid intake primarily to prevent:
  3. Q3. Vincristine, a mitotic inhibitor, is known to cause which specific side effect?
  4. Q4. Which chemotherapy drug is associated with nephrotoxicity and ototoxicity?
  5. Q5. A nurse monitors the WBC count closely in a patient receiving methotrexate because this drug causes:
  6. Q6. Leucovorin is often administered with methotrexate to:
  7. Q7. A patient receiving bleomycin should be monitored for which serious adverse reaction?
  8. Q8. Which chemotherapeutic agent is most likely to cause hemorrhagic cystitis?
  9. Q9. Which of the following best describes the mechanism of action of methotrexate?
  10. Q10. Which chemotherapy agent’s extravasation can cause severe tissue necrosis?
  11. Q11. Which anti-cancer drug is classified as a plant alkaloid?
  12. Q12. Which lab result is most concerning in a patient receiving cytarabine?
  13. Q13. The nurse advises a patient on fluorouracil (5-FU) therapy to report:
  14. Q14. A male patient on bleomycin reports shortness of breath and cough. The nurse suspects:
  15. Q15. Which chemotherapy drug is given intrathecally for CNS involvement?
  16. Q16. Which agent is an estrogen receptor modulator used in breast cancer treatment?
  17. Q17. Which laboratory value is most important to monitor during cisplatin therapy?
  18. Q18. A nurse recognizes that alopecia is a common and reversible side effect of:
  19. Q19. Which nursing intervention is essential for a patient receiving vesicant chemotherapy via IV?
  20. Q20. Which symptom indicates potential neurotoxicity in a patient receiving vincristine?