A nurse explains to a patient that “your cancer is T2N1M0, grade 2”. Which statement best reflects what they should understand?

1. A large tumour with distant metastasis and high-grade cells
2. A moderate tumour, some nodal spread, no distant spread, moderately differentiated
3. A very small tumour, no nodes or spread, but highly abnormal cells
4. The tumour's grade and stage essentially mean the same thing

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