Before entering the Krebs cycle, pyruvate undergoes oxidative decarboxylation to form which 2-carbon compound?
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Correct answer: Acetyl CoA
Pyruvate produced in glycolysis enters the mitochondrial matrix and undergoes oxidative decarboxylation catalyzed by pyruvate dehydrogenase. This 'link reaction' produces Acetyl CoA, which then enters the TCA cycle.
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More Krebs Cycle (TCA): Steps and Significance questions
- Which enzyme complex is responsible for the conversion of Pyruvate to Acetyl CoA?
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