Vaccines and their role · NCERT Biology

The term 'Attenuated' in vaccine science refers to:

  1. Increasing the virulence of a pathogen to enhance immune response
  2. Weakening a pathogen so it replicates without causing disease
  3. Killing the pathogen completely using ultraviolet radiation
  4. Extracting only the surface proteins of the pathogen
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Correct answer: Weakening a pathogen so it replicates without causing disease

Attenuation is the process of weakening a pathogen (usually by passing it through different hosts or cell cultures). The attenuated pathogen is still 'alive' and can replicate to induce an immune response without causing the actual disease.

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