Vaccines and their role · NCERT Biology

The Hepatitis B vaccine currently in use is produced using which of the following?

  1. Live attenuated viral strain
  2. Formalin-inactivated whole virus
  3. Yeast (Recombinant DNA technology)
  4. Purified venom protein extract
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Correct answer: Yeast (Recombinant DNA technology)

The Hepatitis B vaccine is a second-generation subunit vaccine produced via recombinant DNA technology. The gene encoding the viral surface antigen (HBsAg) is expressed in Saccharomyces cerevisiae (yeast), which then produces the antigenic protein in large quantities.

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