Digestive Enzymes: Amylase, Protease, Lipase · NCERT Biology

The inactive enzyme pepsinogen is converted into active pepsin in the stomach by the action of:

  1. Enterokinase
  2. Bile salts
  3. HCl (gastric acid)
  4. Bicarbonate ions
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Correct answer: HCl (gastric acid)

Pepsinogen is a proenzyme secreted by the gastric chief cells. Upon exposure to hydrochloric acid (HCl) secreted by parietal cells, it is converted into the active proteolytic enzyme pepsin, which digests proteins into peptones and proteoses.

Difficulty: Medium Question 2 of 20

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