During a blood transfusion, what is the most critical factor to check to prevent 'clumping' (agglutination) of RBCs?
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Correct answer: Compatibility of antigens and antibodies
Transfusion compatibility depends on matching the donor's antigens with the recipient's antibodies. If incompatible, the antibodies will attack the donor RBCs, causing them to clump together and lyse.
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More Blood Groups and Significance questions
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