Synapses · Histology

Which protein, found on the vesicle membrane, acts as the primary calcium sensor for fusion?

  1. Synaptophysin
  2. Synaptotagmin
  3. Syntaxin
  4. SNAP-25
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Correct answer: Synaptotagmin

Synaptotagmin is a specialized transmembrane protein on synaptic vesicles. It possesses calcium-binding domains that, when occupied, trigger the SNARE complex to complete membrane fusion.

Difficulty: Medium Question 7 of 20

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