Smooth Muscle Histology · Histology

In a smooth muscle cell, where is the single, elongated nucleus typically located?

  1. Pressed against the sarcolemma at the periphery
  2. At the extreme tapering ends of the cell
  3. Smooth muscle cells are multinucleated
  4. At the widest central part of the cell
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Correct answer: At the widest central part of the cell

Unlike skeletal muscle, smooth muscle contains only one nucleus per cell, located centrally at the fiber's widest point. When the cell contracts, the nucleus may take on a 'corkscrew' appearance.

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