Muscle Fibers · Histology

Which of the following describes the nucleus of a skeletal muscle fiber?

  1. Single and centrally located within the cytoplasm
  2. Multiple and centrally located throughout the sarcoplasm
  3. Multiple and peripherally located beneath the sarcolemma
  4. Skeletal muscle fibers do not have nuclei
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Correct answer: Multiple and peripherally located beneath the sarcolemma

Due to the fusion of many myoblasts, skeletal muscle fibers are multinucleated syncytia. The nuclei are pushed to the periphery by the massive volume of organized myofibrils filling the sarcoplasm.

Difficulty: Medium Question 12 of 20

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