Muscle Contraction · Histology

In skeletal muscle, where is the majority of calcium stored during the relaxed state?

  1. In the T-tubules
  2. In the sarcoplasmic reticulum
  3. In the mitochondria
  4. In the rough endoplasmic reticulum
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Correct answer: In the sarcoplasmic reticulum

The sarcoplasmic reticulum is a specialized smooth ER that serves as a reservoir for calcium ions. The terminal cisternae are the specific dilated regions that sit adjacent to T-tubules to form triads.

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