Osteocytes · Histology

Which of the following describes the primary developmental origin of an osteocyte?

  1. Fusion of multiple monocytes
  2. Differentiation of a chondrocyte
  3. An osteoblast trapped in its own secreted matrix
  4. Direct transformation of a mesenchymal stem cell
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Correct answer: An osteoblast trapped in its own secreted matrix

Osteocytes are mature bone cells that originate from osteoblasts. Once an osteoblast surrounds itself with osteoid that subsequently mineralizes, it transitions into an osteocyte residing within a lacuna.

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