Biology

Cell Division Practice Questions

20 free Cell Division practice questions for the General Science. Tap an option to answer — you get instant feedback, the correct answer, and a detailed explanation for every question.

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Question 1 of 20 Medium

In which phase of the cell cycle does DNA replication occur?

  1. A G1 phase
  2. B S phase
  3. C G2 phase
  4. D M phase

Correct answer: S phase

The S phase (Synthesis phase) is the part of interphase during which the cell's DNA is replicated. This ensures that each daughter cell receives a complete and identical set of chromosomes.

Question 2 of 20 Medium

Which of the following occurs during prophase of mitosis?

  1. A Chromosomes line up at the equator
  2. B Sister chromatids separate
  3. C The nuclear envelope breaks down and chromatin condenses
  4. D DNA replication begins

Correct answer: The nuclear envelope breaks down and chromatin condenses

Prophase is the first stage of mitosis where the genetic material condenses into visible chromosomes. During this stage, the nucleolus disappears and the nuclear envelope starts to disintegrate to allow spindle fiber attachment.

Question 3 of 20 Medium

During metaphase, chromosomes are aligned at the center of the cell. What structure is responsible for pulling them into this position?

  1. A Centrioles
  2. B Spindle fibers
  3. C Nuclear membrane
  4. D Cytoskeleton

Correct answer: Spindle fibers

Spindle fibers, composed of microtubules, attach to the kinetochores of the chromosomes. They exert tension from opposite poles to align the chromosomes along the metaphase plate.

Question 4 of 20 Medium

What is the primary result of mitosis in multicellular organisms?

  1. A Production of four haploid daughter cells
  2. B Production of two genetically identical diploid daughter cells
  3. C Increase in genetic variation
  4. D Formation of gametes for reproduction

Correct answer: Production of two genetically identical diploid daughter cells

Mitosis is a form of equational division used for growth, tissue repair, and asexual reproduction. It results in two daughter cells that are genetically identical to each other and the original parent cell.

Question 5 of 20 Medium

Which specific stage of mitosis is characterized by the separation of sister chromatids as they move toward opposite poles?

  1. A Prophase
  2. B Metaphase
  3. C Anaphase
  4. D Telophase

Correct answer: Anaphase

In anaphase, the centromeres split and the sister chromatids are pulled apart by the shortening of the spindle fibers. Once separated, each chromatid is considered an individual chromosome.

Question 6 of 20 Medium

Cytokinesis in plant cells differs from animal cells primarily because plant cells must form a:

  1. A Cleavage furrow
  2. B Cell plate
  3. C Centrosome
  4. D Contractile ring

Correct answer: Cell plate

Due to the rigid cell wall, plant cells cannot pinch inward like animal cells. Instead, vesicles from the Golgi apparatus collect at the midline to form a cell plate, which eventually develops into a new cell wall.

Question 7 of 20 Medium

In meiosis, the process of 'crossing over' occurs during which phase?

  1. A Prophase I
  2. B Metaphase I
  3. C Prophase II
  4. D Anaphase II

Correct answer: Prophase I

Crossing over involves the exchange of genetic material between non-sister chromatids of homologous chromosomes. This happens during Prophase I and is a major source of genetic variation in offspring.

Question 8 of 20 Medium

How many daughter cells are produced at the end of Meiosis II, and what is their ploidy level?

  1. A Two diploid cells
  2. B Two haploid cells
  3. C Four diploid cells
  4. D Four haploid cells

Correct answer: Four haploid cells

Meiosis involves two rounds of division following a single round of DNA replication. This produces four daughter cells, each containing half the number of chromosomes (haploid) as the original parent cell.

Question 9 of 20 Medium

What happens during Telophase of mitosis?

  1. A Chromosomes move to the center of the cell
  2. B Two new nuclear envelopes form around the separated chromosomes
  3. C The cell undergoes DNA synthesis
  4. D Spindle fibers attach to centromeres

Correct answer: Two new nuclear envelopes form around the separated chromosomes

Telophase is the final stage of mitosis where chromosomes reach the poles and begin to de-condense back into chromatin. The nuclear envelope reforms around each set of chromosomes, resulting in two distinct nuclei.

Question 10 of 20 Medium

The region where two sister chromatids are joined together is known as the:

  1. A Centriole
  2. B Centrosome
  3. C Centromere
  4. D Chromatid

Correct answer: Centromere

The centromere is the constricted region of a chromosome that holds sister chromatids together. It also serves as the attachment point for spindle fibers during cell division.

Question 11 of 20 Medium

Which of the following describes 'homologous chromosomes'?

  1. A Identical copies of a single chromosome produced by replication
  2. B Pairs of chromosomes (one from each parent) that carry the same genes
  3. C Chromosomes that have undergone mutation
  4. D The two halves of a single chromatid

Correct answer: Pairs of chromosomes (one from each parent) that carry the same genes

Homologous chromosomes are pairs of chromosomes that are similar in shape, size, and gene position. One is inherited from the mother and one from the father, and they pair up during meiosis.

Question 12 of 20 Medium

What is the significance of Meiosis I being called a 'reduction division'?

  1. A It reduces the size of the cell
  2. B It reduces the number of chromosomes from diploid to haploid
  3. C It reduces the amount of cytoplasm in the cell
  4. D It reduces the rate of cell division

Correct answer: It reduces the number of chromosomes from diploid to haploid

Meiosis I separates homologous chromosomes rather than sister chromatids. This results in the chromosome count being halved (e.g., from 46 to 23 in humans), which is necessary to maintain a constant chromosome number after fertilization.

Question 13 of 20 Medium

Which protein complex regulates the cell cycle checkpoints to ensure the cell is ready for the next phase?

  1. A Hemoglobin
  2. B Cyclins and Cyclin-Dependent Kinases (CDKs)
  3. C Actin and Myosin
  4. D DNA Polymerase

Correct answer: Cyclins and Cyclin-Dependent Kinases (CDKs)

Cyclins and CDKs are the internal regulatory proteins of the cell cycle. They control the transition between phases and can halt the cycle if DNA damage or incomplete replication is detected.

Question 14 of 20 Medium

Uncontrolled cell division that ignores normal regulatory signals often leads to:

  1. A Meiosis
  2. B Apoptosis
  3. C Cancer
  4. D Differentiation

Correct answer: Cancer

Cancer is essentially a disease of the cell cycle. When the genes that regulate cell division mutate, cells may divide continuously, forming masses of cells called tumors.

Question 15 of 20 Medium

In human males, the process of meiosis results in the formation of:

  1. A One functional egg and three polar bodies
  2. B Two identical sperm cells
  3. C Four functional sperm cells
  4. D Four diploid body cells

Correct answer: Four functional sperm cells

Spermatogenesis is the male version of meiosis. It produces four haploid spermatids from a single primary spermatocyte, all of which eventually mature into functional sperm cells.

Question 16 of 20 Medium

What is the state of a cell in the 'G0 phase'?

  1. A Rapidly dividing
  2. B Synthesizing DNA
  3. C A non-dividing, resting state
  4. D Undergoing programmed cell death

Correct answer: A non-dividing, resting state

The G0 phase is a quiescent period where cells exit the cell cycle. Some cells, like neurons, stay in G0 permanently, while others can be signaled to re-enter the cycle for repair or growth.

Question 17 of 20 Medium

During which phase of meiosis do homologous chromosomes separate, while sister chromatids remain attached?

  1. A Anaphase I
  2. B Anaphase II
  3. C Metaphase I
  4. D Metaphase II

Correct answer: Anaphase I

In Anaphase I, the homologous pairs are pulled to opposite poles. Unlike mitotic anaphase, the sister chromatids stay together at their centromeres until Anaphase II.

Question 18 of 20 Medium

The failure of chromosomes to separate properly during meiosis is known as:

  1. A Recombination
  2. B Nondisjunction
  3. C Independent assortment
  4. D Synapsis

Correct answer: Nondisjunction

Nondisjunction occurs when chromosomes fail to separate in either Meiosis I or II. This results in gametes with an abnormal number of chromosomes, which can lead to conditions such as Down Syndrome.

Question 19 of 20 Medium

What is 'independent assortment' during meiosis?

  1. A The random alignment of homologous pairs at the metaphase plate
  2. B The specific way DNA replicates in the S phase
  3. C The movement of sister chromatids to the same pole
  4. D The repair of damaged chromosomes

Correct answer: The random alignment of homologous pairs at the metaphase plate

Independent assortment occurs in Metaphase I when homologous pairs align randomly. Because each pair orients independently of the others, there are millions of possible combinations of maternal and paternal chromosomes in the resulting gametes.

Question 20 of 20 Medium

In animal cells, what structures help organize the assembly of spindle fibers during mitosis?

  1. A Chloroplasts
  2. B Centrosomes containing centrioles
  3. C Nucleoli
  4. D Vacuoles

Correct answer: Centrosomes containing centrioles

Centrosomes act as the main microtubule-organizing centers in animal cells. They duplicate during interphase and move to opposite poles to form the mitotic spindle that orchestrates chromosome movement.

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