Fungi · Botany

Which sterol is a unique component of the fungal plasma membrane and is a common target for antifungal drugs like Amphotericin B?

  1. Cholesterol
  2. Ergosterol
  3. Phytosterol
  4. Stigmasterol
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Correct answer: Ergosterol

Ergosterol performs a similar stabilizing function in fungal membranes as cholesterol does in animal membranes. Because humans lack ergosterol, drugs that bind to it or inhibit its synthesis can selectively kill fungi with minimal toxicity to the host.

Difficulty: Medium Question 6 of 20

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