Mitosis · Botany

Colchicine is a chemical used in botany to induce polyploidy because it inhibits:

  1. Spindle fiber (microtubule) formation
  2. The cellular DNA replication process
  3. The cell wall synthesis enzyme pathway
  4. The cellular glucose metabolism pathway
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Correct answer: Spindle fiber (microtubule) formation

Colchicine binds to tubulin dimers, preventing their polymerization into microtubules. This stops mitosis before anaphase, resulting in a cell with double the chromosome number.

Difficulty: Medium Question 12 of 20

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